PHI-base

PHI-base

The Pathogen - Host Interaction database (PHI-base) contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions. The database was created and is maintained by researchers at Rothamsted Research and external collaborators.

PHI-base (http://www.phi-base.org) was developed to utilise effectively the growing number of verified genes that mediate an organism's ability to cause disease and / or to trigger host responses.

The web-accessible database catalogues experimentally verified pathogenicity, virulence and effector genes from fungal and Oomycete pathogens which infect animal, plant and fungal hosts. PHI-base is the first on-line resource devoted to the identification and presentation of information on fungal and Oomycete pathogenicity genes and their host interactions. As such, PHI-base is a strong valuable resource for the discovery of candidate targets in medically and agronomically important fungal and Oomycete pathogens for intervention with synthetic chemistries and natural products.

Each entry in PHI-base is curated by domain experts and supported by strong experimental evidence (gene disruption experiments) as well as literature references in which the experiments are described. Each gene in PHI-base is presented with its nucleotide and deduced amino acid sequence as well as a detailed structured description of the predicted protein's function during the host infection process. To facilitate data interoperability, genes are annotated using controlled vocabularies (Gene Ontology terms, EC Numbers, etc.), and links to other external data sources (for example, NCBI taxonomy, EMBL and UniProt) are provided.

References

Winnenburg, R., Urban, M., Beacham, A., Baldwin, T.K., Holland, S., Lindeberg, M., Hansen, H., Rawlings, C., Hammond-Kosack, K. and Köhler, J. 2008. PHI-base update: additions to the pathogen host interactions database. "Nucleic Acids Research" 36 (Database Issue): D572-6

Baldwin, T.K., Winnenburg, R., Urban, M., Rawlings, C., Köhler, J. and Hammond-Kosack, K.E. 2006. The Pathogen-Host Interactions database (PHI-base) provides insights into generic and novel themes of pathogenicity. "Molecular Plant-Microbe Interactions" 19(12):1451-62

Winnenburg, R., Baldwin, T.K., Urban, M., Rawlings, C., Köhler, J. and Hammond-Kosack, K.E. 2006. PHI-base: a new database for pathogen host interactions. "Nucleic Acids Research." 34 (Database issue): D459-64


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • Base D'or — En mathématiques, le nombre d or, à savoir peut être utilisé comme une base de numération. Ce système est connu sous le nom base d or, ou accessoirement, phinaire (car le symbole pour le nombre d or est la lettre grecque « phi »). Tout… …   Wikipédia en Français

  • Phi Iota Alpha — ΦIΑ Founded December 26, 1931 (1931 12 26) (79 …   Wikipedia

  • Phi Mu Alpha Sinfonia — ΦΜΑ Founded October 6, 1898 (1898 10 06) (113 years ago) New England Conservatory of Music …   Wikipedia

  • Phi Kappa Psi — (ΦΚΨ, Phi Psi) est une Fraternité étudiante américaine. Sommaire 1 Histoire 2 Profession de foi 3 Symboles 4 L ordre du S.C …   Wikipédia en Français

  • Phi Persei — Données d observation (Époque J2000.0) Ascension droite 01h 43m 39,62s Déclinaison 50° 41′ 19,6″ Constellation Persée Magnitude apparente 4,01 …   Wikipédia en Français

  • Phi Velorum — Données d observation (Époque J2000) Ascension droite 09h 56m 51.8s Déclinaison 54° 34′ 04″ Constellation Voiles Magnitude apparente 3,52 …   Wikipédia en Français

  • Base propre — Valeur propre, vecteur propre et espace propre Fig. 1. Cette application linéaire déforme la statue de David. Les vecteurs bleus ont pour images les vecteurs verts. Ils gardent la même direction, ce sont des vecteurs propres. La valeur propre… …   Wikipédia en Français

  • Base d'or — En mathématiques, le nombre d or, à savoir peut être utilisé comme une base de numération. Ce système est connu sous le nom base d or, ou accessoirement, phinaire (car le symbole pour le nombre d or est la lettre grecque « phi »). Tout… …   Wikipédia en Français

  • Phi Sigma Kappa — Infobox Fraternity | name = Phi Sigma Kappa letters = ΦΣK crest = founded = birth date and age|1873|3|15 birthplace = Massachusetts Agricultural College flagicon|USA type = Social motto = Do unto others as you would have them do unto you. free… …   Wikipedia

  • Phi Kappa Sigma — Infobox Fraternity letters = ΦΚΣ name = Phi Kappa Sigma crest = motto = Stellis Aequus Durando ( Equal to the Stars in Endurance. ) nickname = Phi Kaps, Skulls, or Skullhouse colors = Black and Old Gold symbol = Maltese Cross flower = Yellow… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”