Bismuth subsalicylate

Bismuth subsalicylate

Drugbox
IUPAC_name = 2-Hydroxy-4"H"-1,3,2-benzodioxabismin-4-one


CAS_number = 14882-18-9
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PubChem = 16682734
DrugBank =
chemical_formula = C7H5BiO4
molecular_weight = 362.11 g/mol
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Bismuth subsalicylate, with a chemical formula C7H5BiO4, ["Merck Index", 11th Edition, 1299.] is a drug used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. Bismuth subsalicylate does exhibit antibacterial activity; however, it is not derived from another living biological source, which does not classify it as an 'antibiotic.' Commonly known as pink bismuth, it is the active ingredient in popular medications such as Pepto-Bismol and (modern) Kaopectate.

As a salt of salicylic acid, bismuth salicylate displays anti-inflammatory action and also acts as an antacid.

There are some adverse effects. It can also cause a black tongue and black stools in some users of the drug, when it combines with trace amounts of sulfur in their saliva and gastrointestinal tract. [ [http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607040.html Drug information page] at the National Institutes of Health] This discoloration is temporary and harmless.

Children should not take medication with bismuth subsalicylate while recovering from influenza or chicken pox, as epidemiologic evidence points to an association between the use of salicylate-containing medications during certain viral infections and the onset of Reye's syndrome. [ [http://www.reyessyndrome.org/aspirin.htm Aspirin or Salicylate-Containing Medications] , reyessyndrome.org] For the same reason, it is typically recommended that nursing mothers not use medication containing bismuth subsalicylate (such as Pepto-Bismol) because small amounts of the medication are excreted in breast milk and pose a theoretical risk of Reye's syndrome to nursing children. [ [http://www.cdc.gov/breastfeeding/disease/illness.htm CDC warning about breastfeeding while taking medications] ]

While bismuth is technically radioactive, its half life is so long, on the order of hundreds of billions of years, [cite journal | last = Marcillac | first = Pierre de | coauthors = Noël Coron, Gérard Dambier, Jacques Leblanc, and Jean-Pierre Moalic | year = 2003 | month = April | title = Experimental detection of α-particles from the radioactive decay of natural bismuth | journal = Nature | volume = 422 | pages = 876–878 | doi = 10.1038/nature01541 ] that it is safe for all medical and other ordinary purposes.

References


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Look at other dictionaries:

  • bismuth subsalicylate — bismuth sub·sa·lic·y·late .səb sə lis ə .lāt n an antidiarrheal drug C7H5BiO4 also used to relieve heartburn, indigestion, and nausea see PEPTO BISMOL * * * [USP] a bismuth salt of salicylic acid, administered orally in the treatment of diarrhea… …   Medical dictionary

  • bismuth subsalicylate — noun or bismuth salicylate : a basic salt obtained as a white or nearly white powder of varying composition and sometimes used as an adjuvant to penicillin in the treatment of syphilis …   Useful english dictionary

  • bismuth subsalicylate — noun Date: 1941 a drug C7H5BiO4 taken orally to relieve diarrhea, nausea, and indigestion …   New Collegiate Dictionary

  • Bismuth — (pronEng|ˈbɪzməθ) is a chemical element that has the symbol Bi and atomic number 83. This heavy, brittle, white crystalline trivalent poor metal has a pink tinge and chemically resembles arsenic and antimony. Of all the metals, it is the most… …   Wikipedia

  • bismuth — bismuthal, adj. /biz meuhth/, n. Chem. a brittle, grayish white, red tinged, metallic element used in the manufacture of fusible alloys and in medicine. Symbol: Bi; at. wt.: 208.980; at. no.: 83. [1660 70; earlier bismutum < NL bisemutum,… …   Universalium

  • Bismuth chloride — chembox new ImageFile = ImageSize = IUPACName = Bismuth chloride OtherNames = Bismuth trichloride, Trichlorobismuth, Trichlorobismuthine, Bismuth (III) chloride Formula = BiCl3 Section1 = Chembox Identifiers Abbreviations = CASNo = 7787 60 2… …   Wikipedia

  • subsalicylate — sub·sa·lic·y·late sə lis ə .lāt n a basic salicylate (as bismuth subsalicylate) …   Medical dictionary

  • bismuth salicylate — noun see bismuth subsalicylate …   Useful english dictionary

  • Bismuth subcarbonate — Other names bismuth oxycarbonate, bismuthyl carbonate, bismutite Identifiers CAS number …   Wikipedia

  • Bismuth(III) sulfide — IUPAC name Bismuth(III) sulfide …   Wikipedia

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