Lysosomal lipase

Lysosomal lipase

protein
Name=lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
caption=


width=
HGNCid=6617
Symbol=LIPA
AltSymbols=
EntrezGene=3988
OMIM=278000
RefSeq=NM_000235
UniProt=P38571
PDB=
ECnumber=3.1.1.3
Chromosome=10
Arm=q
Band=23.2
LocusSupplementaryData=-23.3

Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.

Clinical significance

A deficiency is associated with Wolman disease.

Chlorpromazine is an inhibitor of lysosomal lipase.cite journal |author=Sauro VS, Klamut HJ, Lin CH, Strickland KP |title=Lysosomal triacylglycerol lipase activity in L6 myoblasts and its changes on differentiation |journal=Biochem. J. |volume=227 |issue=2 |pages=583–9 |year=1985 |pmid=4004781 |doi=]

References

External links

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