HMGB1

HMGB1

High-mobility group box 1, also known as HMGB1 and Amphoterin, is a human gene and protein that belongs to high mobility group.

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Further reading

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*cite journal | author=Thomas JO, Travers AA |title=HMG1 and 2, and related 'architectural' DNA-binding proteins. |journal=Trends Biochem. Sci. |volume=26 |issue= 3 |pages= 167–74 |year= 2001 |pmid= 11246022 |doi=
*cite journal | author=Andersson U, Erlandsson-Harris H, Yang H, Tracey KJ |title=HMGB1 as a DNA-binding cytokine. |journal=J. Leukoc. Biol. |volume=72 |issue= 6 |pages= 1084–91 |year= 2003 |pmid= 12488489 |doi=
*cite journal | author=Erlandsson Harris H, Andersson U |title=Mini-review: The nuclear protein HMGB1 as a proinflammatory mediator. |journal=Eur. J. Immunol. |volume=34 |issue= 6 |pages= 1503–12 |year= 2004 |pmid= 15162419 |doi= 10.1002/eji.200424916
*cite journal | author=Jiang W, Pisetsky DS |title=Mechanisms of Disease: the role of high-mobility group protein 1 in the pathogenesis of inflammatory arthritis. |journal=Nature clinical practice. Rheumatology |volume=3 |issue= 1 |pages= 52–8 |year= 2007 |pmid= 17203009 |doi= 10.1038/ncprheum0379
*cite journal | author=Ellerman JE, Brown CK, de Vera M, "et al." |title=Masquerader: high mobility group box-1 and cancer. |journal=Clin. Cancer Res. |volume=13 |issue= 10 |pages= 2836–48 |year= 2007 |pmid= 17504981 |doi= 10.1158/1078-0432.CCR-06-1953
*cite journal | author=Fossati S, Chiarugi A |title=Relevance of high-mobility group protein box 1 to neurodegeneration. |journal=Int. Rev. Neurobiol. |volume=82 |issue= |pages= 137–48 |year= 2007 |pmid= 17678959 |doi= 10.1016/S0074-7742(07)82007-1
*cite journal | author=Parkkinen J, Rauvala H |title=Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen activation by amphoterin. |journal=J. Biol. Chem. |volume=266 |issue= 25 |pages= 16730–5 |year= 1991 |pmid= 1909331 |doi=
*cite journal | author=Wen L, Huang JK, Johnson BH, Reeck GR |title=A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. |journal=Nucleic Acids Res. |volume=17 |issue= 3 |pages= 1197–214 |year= 1989 |pmid= 2922262 |doi=
*cite journal | author=Bernués J, Espel E, Querol E |title=Identification of the core-histone-binding domains of HMG1 and HMG2. |journal=Biochim. Biophys. Acta |volume=866 |issue= 4 |pages= 242–51 |year= 1986 |pmid= 3697355 |doi=
*cite journal | author=Ge H, Roeder RG |title=The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein. |journal=J. Biol. Chem. |volume=269 |issue= 25 |pages= 17136–40 |year= 1994 |pmid= 8006019 |doi=
*cite journal | author=Parkkinen J, Raulo E, Merenmies J, "et al." |title=Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation. |journal=J. Biol. Chem. |volume=268 |issue= 26 |pages= 19726–38 |year= 1993 |pmid= 8366113 |doi=
*cite journal | author=Ferrari S, Finelli P, Rocchi M, Bianchi ME |title=The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13. |journal=Genomics |volume=35 |issue= 2 |pages= 367–71 |year= 1996 |pmid= 8661151 |doi= 10.1006/geno.1996.0369
*cite journal | author=Zappavigna V, Falciola L, Helmer-Citterich M, "et al." |title=HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. |journal=EMBO J. |volume=15 |issue= 18 |pages= 4981–91 |year= 1996 |pmid= 8890171 |doi=
*cite journal | author=Xiang YY, Wang DY, Tanaka M, "et al." |title=Expression of high-mobility group-1 mRNA in human gastrointestinal adenocarcinoma and corresponding non-cancerous mucosa. |journal=Int. J. Cancer |volume=74 |issue= 1 |pages= 1–6 |year= 1997 |pmid= 9036861 |doi=
*cite journal | author=Rasmussen RK, Ji H, Eddes JS, "et al." |title=Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2. |journal=Electrophoresis |volume=18 |issue= 3-4 |pages= 588–98 |year= 1997 |pmid= 9150946 |doi= 10.1002/elps.1150180342
*cite journal | author=Jayaraman L, Moorthy NC, Murthy KG, "et al." |title=High mobility group protein-1 (HMG-1) is a unique activator of p53. |journal=Genes Dev. |volume=12 |issue= 4 |pages= 462–72 |year= 1998 |pmid= 9472015 |doi=
*cite journal | author=Milev P, Chiba A, Häring M, "et al." |title=High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule. |journal=J. Biol. Chem. |volume=273 |issue= 12 |pages= 6998–7005 |year= 1998 |pmid= 9507007 |doi=
*cite journal | author=Nagaki S, Yamamoto M, Yumoto Y, "et al." |title=Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks. |journal=Biochem. Biophys. Res. Commun. |volume=246 |issue= 1 |pages= 137–41 |year= 1998 |pmid= 9600082 |doi= 10.1006/bbrc.1998.8589
*cite journal | author=Claudio JO, Liew CC, Dempsey AA, "et al." |title=Identification of sequence-tagged transcripts differentially expressed within the human hematopoietic hierarchy. |journal=Genomics |volume=50 |issue= 1 |pages= 44–52 |year= 1999 |pmid= 9628821 |doi= 10.1006/geno.1998.5308
*cite journal | author=Boonyaratanakornkit V, Melvin V, Prendergast P, "et al." |title=High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells. |journal=Mol. Cell. Biol. |volume=18 |issue= 8 |pages= 4471–87 |year= 1998 |pmid= 9671457 |doi=

External links

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