Rheumatoid nodule

Rheumatoid nodule

A rheumatoid nodule is a collection of normal cells including lymphocytes, and fibroblasts that surround a center of fibrinoid necrosis. They are usually subcutaneous especially over boney prominences such in the olecranon. About 5% of rheumatoid arthritis patients have such nodules within 2 years of disease onset, and the cumulative prevalence is about 25%. [cite journal
author=Carmona L, González-Alvaro I, Balsa A, Angel Belmonte M, Tena X, Sanmartí R |title=Rheumatoid arthritis in Spain: occurrence of extra-articular manifestations and estimates of disease severity |journal=Ann. Rheum. Dis. |volume=62 |issue=9 |pages=897–900 |year=2003 |month=Sep |pmid=12922967 |pmc=1754657
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